Alisson missed Liverpool’s Champions League last-16 first leg defeat at Galatasaray on 10 March with what was described as a “minor” issue, with Mamardashvili standing in.
But he returned for Sunday’s draw against Tottenham and the 4-0 victory over Galatasaray in the second leg on Wednesday.
He previously missed eight Liverpool matches across October and November because of a hamstring injury.
Mamardashvili has featured 12 times for Liverpool in all competitions this season.
Liverpool are fifth in the Premier League table, looking to secure Champions League qualification for next season, while Brighton are 12th.
